No one knows just what causes fibromyalgia. Some possible triggers might include: Using two separate drugs to shed weight can be very effective you'll find combinations in front of the FDA now awaiting approval. When dealing with weight-loss and the people that go through it one should err assisting caution and allow the FDA do its job and demand some study be done so your public knows the side effects and perils associated with the medications before we drive them. Keep in mind that drug companies will be in business to earn money and that they would say almost anything to keep people on the medications. Researchers discovered that participants investing in this drug for the year, lost excess weight within a month and have kept the extra weight off during the entire 56 weeks with the study. Contrave is a combination of the drugs naltrexone and bupropion, which seems to reflect a fresh trend of weight-loss drugs which might be made up of multiple active ingredient, which may make them more effective and safer. Combo-pilling is the newest fad or even better the newest to come under scrutiny and so it is just more publicly known in recent months, comb-pilling to lose weight has been around since the eighties. The biggest reason that utilizing a combination of pills is now popular will be the fact that at the time of right now there aren't any long term prescription weightloss pills that have been licensed by the FDA other than orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications even though some of the combinations are actually rejected or have yet to be licensed by the FDA. Seizures can be a side effect with Contrave and shouldn't be taken in individuals with seizure disorders. The drug could also raise blood pressure level and heart rate, and really should not be used in people with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise blood pressure and heartbeat and must 't be used in patients with uncontrolled high blood pressure level, in addition to by a person with heart-related and cerebrovascular (blood vessel dysfunction impacting mental performance) disease. Patients with a history of heart attack or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes using a boxed warning to alert health care professionals and patients on the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stop smoking. --Participating in support groups that assist the family from the addict recover (like Al-Anon or Nar-Anon).